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By: Aashay Edwin Maghi (CPT)
Researchers still don’t fully understand PCOS’s origins. It likely stems from genetic, hormonal, and environmental factors interacting uniquely in each woman.
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Up to 70 % of women with PCOS have insulin resistance—cells fail to use blood sugar properly. High insulin levels force ovaries to make more testosterone, disrupting ovulation and causing symptoms.
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When insulin spikes, it signals ovaries to release extra androgens (male hormones). This excess testosterone leads to cysts, irregular periods, acne, and excess hair growth.
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PCOS often runs in families—daughters of women with PCOS face higher risk. Researchers have identified at least 19 gene variants linked to PCOS risk, though more remain undiscovered.
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Variants in genes like FSHR, LH, and insulin receptor affect ovarian function and hormone levels. These inherited changes can alter how cells respond to insulin and reproductive hormones, increasing PCOS likelihood
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Beyond genes, diet and environmental toxins can spark PCOS. Inflammatory foods, endocrine disruptors (e.g., BPA), and chronic stress further upset hormone balance and insulin sensitivity.
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Dysbiosis (gut imbalance) in PCOS can worsen insulin resistance and inflammation. High‑inflammatory diets (processed foods, sugar) also feed systemic inflammation, encouraging PCOS symptoms to flare
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Abnormal LH (luteinizing hormone) levels from the pituitary gland disrupt normal ovary function. This hormonal miscommunication prevents regular egg release and contributes to ovarian cyst formation.
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PCOS arises from a “perfect storm” of insulin resistance, genetics, and environmental triggers working together. Understanding these causes helps you tackle PCOS through targeted diet, exercise, and medical care.
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If you suspect PCOS, due to irregular cycles or weight gain, ask your doctor for insulin and hormone tests plus an ultrasound. Adopting a low‑GI diet, regular moderate exercise, and stress management can reduce symptoms and restore balance.
Image: Freepik
Image: Freepik
By: Aashay Edwin Maghi (CPT)